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Solid-phase photochemical C-S bond cleavage of thioethers-a new approach to the solid-phase production of non-peptide molecules

✍ Scribed by Irving Sucholeiki


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
307 KB
Volume
35
Category
Article
ISSN
0040-4039

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A rapid and efficient one-step synthesis of N-protected fl-amino dimethylhydroxamates starting from diazo ketones is reported A Fmoc-protected fl-amino aldehyde obtained by reduction of its corresponding dimethylhydroxamate was incorporated during solid phase assembly of an antigenic peptide. The re