## Abstract For Abstract see ChemInform Abstract in Full Text.
Solid-Phase Oligosaccharide Synthesis of a Small Library of N-Glycans
β Scribed by Simon Jonke; Ke-gang Liu; Richard R. Schmidt
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 586 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0947-6539
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π SIMILAR VOLUMES
Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.
The new lactosyl donor 8, bearing an Fmoc-protected hydroxy group, has been prepared from lactose for the solidphase synthesis of lactose-containing oligosaccharides. In addition to the preparation of 3b-O-fucosyllactoside 1 (with donor 4), use of this new building block has permitted the syntheses
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