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Solid-phase based total synthesis of Jasplakinolide by ring-closing metathesis

✍ Scribed by Tannert, René; Hu, Tai-Shan; Arndt, Hans-Dieter; Waldmann, Herbert


Book ID
120666664
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
604 KB
Volume
12
Category
Article
ISSN
1359-7345

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Racemic and enantiopure targets containing the 6,8-dioxabicycio [3.2.1]octane skeleton, can be conveniently synthesized from monocyclic diene precursors using an intramolecular ruthenium-catalyzed ring-closing metathesis reaction as the key step.