In mammalian cells, nucleoside transport usually is mediated by facilitated diffusion. In addition, a Na(+)-dependent, concentrative nucleoside transport system has been detected in several tissues but not the liver. To further clarify hepatic nucleoside transport mechanisms, we measured the uptake
Sodium purine nucleoside transporter
โ Scribed by Irwin M. Arias
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 18 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The biochemical features of two families with purine nucleoside phosphorylase deficiency are compared. Laboratory studies and an evaluation of kinetic and physical properties of erythrocyte purine nucleoside phosphorylase give evidence that a) the degree of abnormality in uric acid and
The synthesis of a number of novel purine ribonucleosides bearing one degree of unsaturation at the P-position is described. The two key reactions used in the synthesis of these compounds is a palladium-catalyzed cross-coupling reaction and an ozonolysis. These synthetic transformations have rarely
Purine nucleoside phosphorylase deficiency is an inherited disease of purine metabolism characterized clinically as combined immunodeficiency. The molecular defects have been published for 4 different alleles in 3 patients. We report four new mutations including two amino acid substitutions, A 174P