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Snail regulates p21WAF/CIP1 expression in cooperation with E2A and Twist

✍ Scribed by Eishi Takahashi; Noriko Funato; Norihisa Higashihori; Yuiro Hata; Thomas Gridley; Masataka Nakamura

Book ID: 116289490
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 904 KB
Volume: 325
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2004.10.148

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Data are non-existent regarding coincidental alterations in the expression of p53 and its downstream target genes MDM2 and p21 Waf1/Cip1 in gastric carcinogenesis. An immunohistochemical study was therefore performed to examine the interrelationships of p53, MDM2, and p21 Waf1/Cip1 expression in a s