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Small molecule inhibitors of dual specificity protein phosphatases

✍ Scribed by Pestell, Katharine E; Ducruet, Alexander P; Wipf, Peter; Lazo, John S

Book ID: 110064389
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 154 KB
Volume: 19
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1204084

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## Abstract Protein tyrosine phosphatases (PTPs), a large family of signaling enzymes, play essential roles in intracellular signal transduction by regulating the cellular level of tyrosine phosphorylation to control cell growth and differentiation, metabolism, cell migration, gene transcription, i