ChemInform Abstract: Sulfonylated Aminothiazoles as New Small Molecule Inhibitors of Protein Phosphatases.
β Scribed by Peter Wipf; Diana C. Aslan; Eileen C. Southwick; John S. Lazo
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 28 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Naphthalenebis [Ξ±,Ξ±-difluoromethylenephosphonates] as Potent Inhibitors of Protein Tyrosine Phosphatases. -The desired disubstituted naphthalenes are better protein tyrosine phosphatase inhibitors than the monosubstituted ones. Derivatives (I)-(III) are the most potent inhibitors yet reported. -(WA