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Slight promotion effects of intermittent administration of testosterone propionate and/or diethylstilbestrol on 3,2′-dimethyl-4-aminobiphenyl-initiated rat prostate carcinogenesis

✍ Scribed by Lin Cui; Toshio Mori; Satoru Takahashi; Katsumi Imaida; Keisuke Akagi; Hideaki Yada; Makoto Yaono; Tomoyuki Shirai


Book ID
117468679
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
45 KB
Volume
122
Category
Article
ISSN
0304-3835

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## Background: Our previous data suggest that estrogen plays an important role in rat prostate carcinogenesis, particularly in promotion by testosterone. therefore, in the present experiment, effects of an antiestrogen, tamoxifen (tam), were investigated. ## Methods: Male f344 rats initially rece