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Direct Effects of Testosterone, Dihydrotestosterone and Estrogen on 3,2′-Dimethyl-4-aminobiphenyl-induced Prostate Carcinogenesis in Castrated F344 Rats

✍ Scribed by Mori, Toshio ;Cui, Lin ;Kato, Koji ;Takahashi, Satoru ;Imaida, Katsumi ;Iwasaki, Shogo ;Ito, Nobuyuki ;Shirai, Tomoyuki

Book ID
108581210
Publisher
Wiley (Blackwell Publishing)
Year
1996
Tongue
English
Weight
287 KB
Volume
87
Category
Article
ISSN
0910-5050

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Effects of tamoxifen, an antiestrogen, o
Effects of tamoxifen, an antiestrogen, on rat prostate carcinogenesis by 3,2′-dimethyl-4-aminobiphenyl and testosterone do not support an estrogen role in testosterone promotion
✍ Miyata, Emiko; Kawabe, Mayumi; Sano, Masashi; Takesada, Yasuko; Takahashi, Sator 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 227 KB

## Background: Our previous data suggest that estrogen plays an important role in rat prostate carcinogenesis, particularly in promotion by testosterone. therefore, in the present experiment, effects of an antiestrogen, tamoxifen (tam), were investigated. ## Methods: Male f344 rats initially rece