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Promoting effects of antiandrogenic agents on rat ventral prostate carcinogenesis induced by 3,2′-dimethyl-4-aminobiphenyl (DMAB)

✍ Scribed by Akaza, H; Tsukamoto, S; Morita, T; Yamauchi, A; Onozawa, M; Shimazui, T; Ideyama, Y; Shirai, T

Book ID: 110073208
Publisher: Nature Publishing Group
Year: 2000
Tongue: English
Weight: 86 KB
Volume: 3
Category: Article
ISSN: 1365-7852
DOI: 10.1038/sj.pcan.4500409

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## Background: Our previous data suggest that estrogen plays an important role in rat prostate carcinogenesis, particularly in promotion by testosterone. therefore, in the present experiment, effects of an antiestrogen, tamoxifen (tam), were investigated. ## Methods: Male f344 rats initially rece