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SLE-associated transverse myelitis successfully treated with Rituximab (anti-CD20 monoclonal antibody)

✍ Scribed by D. J. Armstrong; M. T. McCarron; G. D. Wright

Book ID
106007009
Publisher
Springer
Year
2005
Tongue
English
Weight
122 KB
Volume
26
Category
Article
ISSN
0172-8172

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Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have