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Skeletal diversity construction via a branching synthetic strategy

✍ Scribed by Wyatt, Emma E.; Fergus, Suzanne; Galloway, Warren R. J. D.; Bender, Andreas; Fox, David J.; Plowright, Alleyn T.; Jessiman, Alan S.; Welch, Martin; Spring, David R.

Book ID
111916688
Publisher
Royal Society of Chemistry
Year
2006
Tongue
English
Weight
389 KB
Volume
31
Category
Article
ISSN
1359-7345

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Synthetic Strategy toward Skeletal Diver
Synthetic Strategy toward Skeletal Diversity via Solid-Supported, Otherwise Unstable Reactive Intermediates
✍ Steven J. Taylor; Alexander M. Taylor; Stuart L. Schreiber πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 200 KB

Herein we report a new diversity-oriented synthetic pathway to skeletally diverse alkaloid-like compounds from simple, readily available starting materials. The synthetic strategy involves the generation and isolation of reactive, otherwise unstable dihydropyridines and dihydroisoquinolines on a sol