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Skeletal Diversity Construction via a Branching Synthetic Strategy.

✍ Scribed by Emma E. Wyatt; Suzanne Fergus; Warren R. J. D. Galloway; Andreas Bender; David J. Fox; Alleyn T. Plowright; Alan S. Jessiman; Martin Welch; David R. Spring

Book ID
101991642
Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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Synthetic Strategy toward Skeletal Diver
Synthetic Strategy toward Skeletal Diversity via Solid-Supported, Otherwise Unstable Reactive Intermediates
✍ Steven J. Taylor; Alexander M. Taylor; Stuart L. Schreiber πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 200 KB

Herein we report a new diversity-oriented synthetic pathway to skeletally diverse alkaloid-like compounds from simple, readily available starting materials. The synthetic strategy involves the generation and isolation of reactive, otherwise unstable dihydropyridines and dihydroisoquinolines on a sol