Synthetic Strategy toward Skeletal Diversity via Solid-Supported, Otherwise Unstable Reactive Intermediates

Synthetic Strategy toward Skeletal Diver

✍ Steven J. Taylor; Alexander M. Taylor; Stuart L. Schreiber 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 200 KB

Herein we report a new diversity-oriented synthetic pathway to skeletally diverse alkaloid-like compounds from simple, readily available starting materials. The synthetic strategy involves the generation and isolation of reactive, otherwise unstable dihydropyridines and dihydroisoquinolines on a sol