## Abstract The effect of protoporphyrin on erythroid, myeloid and lymphoid leukemic cells and their destruction induced by the photoactivated porphyrin was studied. Friend erythroleukemic cells (FL) and myelocytic leukemic cells (ML) accumulated protoporphyrin in a cap or patchβlike pattern observ
Sites of photosensitization by protoporphyrin and tin protoporphyrin in leukemia L1210 cells
β Scribed by David Kessel; Veronique Schulz
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 283 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1011-1344
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β¦ Synopsis
Studies with protoporphyrin (PP) and tin protoporphyrin (SnPP) were carried out to assess the effects of tin insertion on the sites of dye localization. Fluorescence emission spectra and studies on the sites of photodamage were consistent with a concentration of PP at membrane loci. In contrast, SnPP photodamage involved an intracellular site.
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