Sister-chromatid exchanges in lymphocytes from methimazole-induced hypothyroid mice
β Scribed by W.K. Liu; K.W. Tsui; K.W.H. Lai; Y. Xie
- Book ID
- 113194454
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 444 KB
- Volume
- 326
- Category
- Article
- ISSN
- 0027-5107
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Sister chromatid exchange points (SCE points) on individual chromosomes were studied in cultured lymphocytes from 11 monozygotic (MZ) and nine dizygotic (DZ) same-sexed pairs by means of sequential Q-banding and BUdR-Giemsa techniques. No statistically significant variation between unrelated individ
Cultured lymphocytes from 9 patients with clinically different types of xeroderma pigmentosum were exposed to ultraviolet light at 24 h. An increased rate of sister chromatid exchanges were observed in 6 patients (128--148% increase in three, 34--51% in three), but not in three patients with deSanct