𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Sister chromatid exchanges in cultured peripheral lymphocytes from twins

✍ Scribed by C. Pedersen; Eva Oláh; U. Merrild

Publisher
Springer
Year
1979
Tongue
English
Weight
690 KB
Volume
52
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.

✦ Synopsis

Sister chromatid exchange points (SCE points) on individual chromosomes were studied in cultured lymphocytes from 11 monozygotic (MZ) and nine dizygotic (DZ) same-sexed pairs by means of sequential Q-banding and BUdR-Giemsa techniques. No statistically significant variation between unrelated individuals with respect to SCE points on specific chromosomes was found. Intrapair differences in the number of SCE points on specific chromosomes were not significantly smaller between MZ twin partners as compared with DZ partners. The results suggest that genetic factors do not play any major role in the frequency and distribution of SCE in normal subjects.

📜 SIMILAR VOLUMES

Nitroimidazole derivatives: non-randomne
Nitroimidazole derivatives: non-randomness sister chromatid exchanges in human peripheral blood lymphocytes
✍ Marta Ana Carballo; Romari Alejandra Martinez; Marta Dolores Mudry 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB

## Abstract Nitroimidazole derivatives exhibited genotoxic effect in different experimental conditions. This study focuses on an evaluation of possible genomic targets, at a chromosomal level, of two 5‐nitroimidazoles (ornidazole and metronidazole) using the __in vitro__ human peripheral blood cult

Reduced frequency of sister chromatid ex
Reduced frequency of sister chromatid exchanges in human lymphocytes cultured with autologous serum
✍ P. K. Ghosh; Reita Nand 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 203 KB

The incidence of sister chromatid exchange (SCE) was determined in human lymphocytes cultured with fetal calf, human AB, and autologous serum. In each individual studied, cells grown in medium supplemented with fetal calf and human AB serum showed higher yields of SCE than those cultured with autolo

Analysis of the frequency and distributi
Analysis of the frequency and distribution of sister chromatid exchanges in cultured human lymphocytes
✍ Peter E. Crossen; Maximo E. Drets; Frances E. Arrighi; Dennis A. Johnston 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 409 KB

Lymphocytes from 20 notmal subjects (11 male and 9 female) were examined for the frequency and location of sister chromatid exchanges (SCE) by the BrdU--Giemsa method. The mean frequency of SCE was 6.37 with little significant variation. One subject had a high number of exchanges in chromosome 1 whi