𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs

✍ Scribed by Eny Maria Goloni-Bertollo; Eloiza Helena Tajara; Antonio José Manzato; Marileila Varella-Garcia

Publisher
John Wiley and Sons
Year
1992
Tongue
French
Weight
405 KB
Volume
50
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals were compared with I 5 nurses working in other hospital units and to a control sample matched by sex and age. This points to the need for emphasizing protective measures in the handling of anti-neoplastic agents.

📜 SIMILAR VOLUMES

Chromosomal aberrations, sister chromati
Chromosomal aberrations, sister chromatid exchanges, and urinary thioethers in nurses handling antineoplastic drugs
✍ Dr. Franco Sarto; Andrea Trevisan; Rosella Tomanin; Arianna Canova; Mario Fioren 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 382 KB

## Abstract In this study we examined the structural chromosomal aberrations (CA) and sister chromatid exchanges (SCE) of 12 nurses handling moderate quantities of antineoplastic drugs. Urinary thioethers were also measured to assess the potential exposure to alkyl‐ating drugs. Two control groups w

Sister chromatid exchanges and chromosom
Sister chromatid exchanges and chromosomal aberrations in lymphocytes of nurses handling cytostatic agents
✍ Simone Benhamou; Jacques Pot-Deprun; Hélène Sancho-Garnier; Ivan Chouroulinkov 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 423 KB

A cohort study of 29 nurses who constantly handled cytostatic drugs, and 29 controls matched according to sex and age, was carried out between 1983 and 1986. Cytogenetic damage was assessed by sister chromatid exchanges (SCE) and chromosomal aberrations. No significant increase in mean number of SCE

Quinoline-induced chromosome aberrations
Quinoline-induced chromosome aberrations and sister chromatid exchanges in rat liver
✍ Shoji Asakura; Shigeki Sawada; Tadakazu Sugihara; Hirohiko Daimon; Fumio Sagami 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 80 KB

Induction of chromosome aberrations and sister Treatment with 28 repeated doses of Q induced chromatid exchanges (SCEs) was studied in hepato-significant chromosome aberrations and SCEs dosecytes of F344 rats exposed in vivo to the hepatocar-dependently. Cytogenetic damage induced in the cinogen qui

The genotoxic effect of potassium metabi
The genotoxic effect of potassium metabisulfite using chromosome aberration, sister chromatid exchange, micronucleus tests in human lymphocytes and chromosome aberration test in bone marrow cells of rats
✍ Ayse Yavuz-Kocaman; Eyyup Rencuzogullari; Hasan Basri Ila; Mehmet Topaktas 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 98 KB 👁 2 views

## Abstract Potassium metabisulfite (PMB) is used as an antimicrobial substance in many kinds of foods. In the present study, the effects of PMB on chromosome aberrations (CAs), sister chromatid exchanges (SCEs), and micronucleus (MN) formation in human lymphocytes and as well as its effect on CAs

Increased frequency of sister chromatid
Increased frequency of sister chromatid exchanges in lymphocytes of breast cancer patients
✍ Sidharth G. Adhvaryu; Urwashi M. Rawal; Jayesh V. Patel; Devendra D. Patel; Damo 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 431 KB

Spontaneous and mitomycin-C (MMC)-induced rates of sister chromatid exchanges (SCEs) were studied in peripheral blood lymphocytes (PBLs) of 40 patients with cancer of the breast and 40 healthy female volunteers as controls. Spontaneous SCE per cell value in PBL cultures was 7.72 for the breast cance