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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) presenting with skeletal lesions

✍ Scribed by M. Sundaram; Daphne deMello; Stephanie Falbo; Robert J. Fallon


Publisher
Springer
Year
1998
Tongue
English
Weight
241 KB
Volume
27
Category
Article
ISSN
0364-2348

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Langerhans' cell histiocytosis (LCH) is a clonal proliferation of Langerhans cells (LC) showing histologically an abundant reactive infiltrate composed of macrophages and lymphocytes, as well as eosinophilic and neutrophilic granulocytes. Rosai-Dorfman disease (RDD) shows a sinusoidal accumulation o