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Single nucleotide polymorphisms in the human complement C6 and C7 genes

✍ Scribed by Hiroaki Nishimukai; Koji Nishimura; Chitoshi Orimoto; Tatsuyuki Okiura; Kenji Fujii; Yasuo Fukumori; Shinji Harihara


Book ID
108489896
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
57 KB
Volume
5
Category
Article
ISSN
1344-6223

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A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i