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AnNcoI polymorphism in the human complement component 7 (C7) gene

✍ Scribed by T. Horiuchi; Hiroaki Nishizaka; Hiroshi Tsukamoto; Shin-ichi Harashima; Takuya Sawabe; Chika Morita; Yoshiyuki Niho

Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
56 KB
Volume
44
Category
Article
ISSN
1435-232X

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DNA polymorphism of the human complement
DNA polymorphism of the human complement component C7 gene in familial deficiencies
✍ Eliecer Coto; Eduardo MartΓ­nez-Naves; Orlando DomΓ­nguez; Carlos LΓ³pez-Larrea πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 207 KB

A C7 cDNA probe detecting a TaqI restriction fragment length polymorphism has been used to examine the segregation of the "silent allele" (C7\*Q0) in two familial deficiencies. Carrier diagnosis in healthy children is possible when both parents are heterozygotes. Only one of these two families was i