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Single nucleotide polymorphism—disease relationships: statistical issues for the performance of association studies

✍ Scribed by Nikolaus Becker; Alexandra Nieters; Werner Rittgen

Book ID
114070711
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
84 KB
Volume
525
Category
Article
ISSN
0027-5107

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## Abstract Single nucleotide polymorphisms (SNPs) are becoming widely used as genotypic markers in genetic association studies of common, complex human diseases. For such association screens, a crucial part of study design is determining what SNPs to prioritize for genotyping. We present a novel p