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Sequence-Based Prioritization of Nonsynonymous Single-Nucleotide Polymorphisms for the Study of Disease Mutations

✍ Scribed by Rui Jiang; Hua Yang; Linqi Zhou; C.-C. Jay Kuo; Fengzhu Sun; Ting Chen


Book ID
117855236
Publisher
American Society of Human Genetics
Year
2007
Tongue
English
Weight
976 KB
Volume
81
Category
Article
ISSN
0002-9297

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## Abstract Single nucleotide polymorphisms (SNPs) are becoming widely used as genotypic markers in genetic association studies of common, complex human diseases. For such association screens, a crucial part of study design is determining what SNPs to prioritize for genotyping. We present a novel p