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Single dose pharmacokinetics of fenspiride hydrochloride: phase I clinical trial

โœ Scribed by B. Montes; M. Catalan; A. Roces; J. P. Jeanniot; J. M. Honorato


Publisher
Springer
Year
1993
Tongue
English
Weight
339 KB
Volume
45
Category
Article
ISSN
0031-6970

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Phase I trial of 4-demethoxydaunorubicin
โœ S. Kaplan; C. Sessa; Y. Willems; M. A. Pacciarini; V. Tamassia; F. Cavalli ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer US ๐ŸŒ English โš– 454 KB

Twenty-four patients with a variety of solid tumors entered a Phase I trial with 4-demethoxydaunorubicin, a new analogue of daunorubicin. The drug was given as a single oral dose of 10-60 mg/m 2 repeated every 3-4 weeks. Leukopenia was the dose-limiting toxicity. Other toxic effects included mild t