Simultaneous quantification of Δ9-tetrahydrocannabinol, 11-nor-9-carboxy-tetrahydrocannabinol, cannabidiol and cannabinol in oral fluid by microflow-liquid chromatography–high resolution mass spectrometry
✍ Scribed by Concheiro, Marta; Lee, Dayong; Lendoiro, Elena; Huestis, Marilyn A.
- Book ID
- 123365999
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 509 KB
- Volume
- 1297
- Category
- Article
- ISSN
- 1873-3778
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## Abstract A rapid and sensitive method for the simultaneous confirmatory analysis of three forensic most relevant cannabinoids, Δ^9^‐tetrahydrocannabinol (THC), 11‐hydroxy‐Δ^9^‐tetrahydrocannabinol (11‐OH‐THC) and 11‐nor‐9‐carboxy‐Δ^9^‐tetrahydrocannabinol (THC‐COOH), by means of high‐performance
A method was developed for quantitating 9-carboxy-ll-nor-A'-tetrahydrocannabinol in human urine as part of the process for validating an automated enzyme immunoassay for marijuana metabolites. Sample cleanup was accomplished using a mixed-mode solid-phase extraction. 9-Carboxy-ll-nor-A'-tetrahydroca