## Abstract A rapid and sensitive method for the simultaneous confirmatory analysis of three forensic most relevant cannabinoids, Δ^9^‐tetrahydrocannabinol (THC), 11‐hydroxy‐Δ^9^‐tetrahydrocannabinol (11‐OH‐THC) and 11‐nor‐9‐carboxy‐Δ^9^‐tetrahydrocannabinol (THC‐COOH), by means of high‐performance
Simultaneous determination of Δ9-tetrahydrocannabinol and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in oral fluid using isotope dilution liquid chromatography tandem mass spectrometry
✍ Scribed by Pin Duo Lee; Yuan-Jhe Chang; Keh-Liang Lin; Yan-Zin Chang
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 301 KB
- Volume
- 402
- Category
- Article
- ISSN
- 1618-2650
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A method was developed for quantitating 9-carboxy-ll-nor-A'-tetrahydrocannabinol in human urine as part of the process for validating an automated enzyme immunoassay for marijuana metabolites. Sample cleanup was accomplished using a mixed-mode solid-phase extraction. 9-Carboxy-ll-nor-A'-tetrahydroca
Results obtained from three commercial immunoassay kits, Abuscreen, TDx, and EMIT, commonly used for the initial test of urine cannabinoids (and metabolites) were correlated with the 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (9-THC-COOH) concentration as determined by GC/MS. Correlation