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Simultaneous occurrence of the JAK2V617F mutation and BCR-ABL gene rearrangement in patients with chronic myeloproliferative disorders

✍ Scribed by Yeo-Kyeoung Kim; Myung-Geun Shin; Hye-Ran Kim; Deok-Hwan Yang; Sang-Hee Cho; Je-Jung Lee; Ik-Joo Chung; Dong-Wook Ryang; Hyeoung-Joon Kim

Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
284 KB
Volume
32
Category
Article
ISSN
0145-2126

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Correlations of JAK2–V617F mutation with
Correlations of JAK2–V617F mutation with clinical and laboratory findings in patients with myeloproliferative disorders
✍ Matthaios Speletas; Eirini Katodritou; Chrisoula Daiou; Eudokia Mandala; Emmanou πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 212 KB

Recently, the acquired mutation JAK2-V617F has been described in the majority of patients with myeloproliferative disorders (MPDs). In this study we evaluated its clinical and laboratory correlates in 166 patients with MPDs. The mutation was detected by allele-specific PCR in 119 patients: 81.4% (35

Detection of BCR/ABL gene rearrangement
Detection of BCR/ABL gene rearrangement and the elimination of rearranged clone in chronic myelocytic leukemia patients
✍ Eren, E.; Aytac, U.; Tetik, E.; Akman, O.; Kansu, E.; Gunduz, U. πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 181 KB πŸ‘ 3 views

Cytogenetic and molecular studies were performed on 20 interferon-␣ receiving Turkish chronic myelocytic leukemia patients. Four different restriction endonucleases and bcr-G probe were used for southern blot analysis to detect rearrangements of the bcr gene. The RT-PCR method was also applied to de