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Simultaneous mutation scanning and genotyping by high-resolution DNA melting analysis

โœ Scribed by Palais, Robert; Zhou, Luming; Montgomery, Jesse; Wittwer, Carl T

Book ID
109946113
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
376 KB
Volume
2
Category
Article
ISSN
1750-2799

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Mutation scanning using high-resolution melting curve analysis (HR-melt) is an effective and sensitive method to detect sequence variations. However, the presence of a common SNP within a mutation scanning amplicon may considerably complicate the interpretation of results and increase the number of