High-Resolution DNA Melting Analysis for Simultaneous Mutation Scanning and Genotyping in Solution
โ Scribed by Zhou, L.
- Book ID
- 118137754
- Publisher
- American Association for Clinical Chemistry
- Year
- 2005
- Tongue
- English
- Weight
- 61 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0009-9147
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๐ SIMILAR VOLUMES
Mutation scanning using high-resolution melting curve analysis (HR-melt) is an effective and sensitive method to detect sequence variations. However, the presence of a common SNP within a mutation scanning amplicon may considerably complicate the interpretation of results and increase the number of
High Resolution Melting Analysis (HRMA) is a rapid and sensitive method for single nucleotide polymorphism (SNP) analysis. In the present study we present a novel HRMA assay to detect three SNPs in close proximity of each other in the first exon of the gene encoding mannose-binding lectin (MBL), a k