Carbamazepine-lO,l l-epoxide is a metabolite of carbamazepine that has been identified in the urine OT the rat and in the urine and plasma of marV and which, in the rat, has been shown to have antiepileptic properties comparable to those of the parent drug. It has therefore been suggested3 that, in
✦ LIBER ✦
Simultaneous determination of zonisamide, carbamazepine and carbamazepine-10,11-epoxide in infant serum by high-performance liquid chromatography
✍ Scribed by Terumitsu Yoshida; Koichi Imai; Sumiko Motohashi; Shin-ichiro Hamano; Masato Sato
- Book ID
- 111713313
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 214 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0731-7085
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## Abstract A high‐performance liquid chromatography assay with ultraviolet detection was developed for the simultaneous determination of the anti‐epileptic drugs lamotrigine, carbamazepine and zonisamide in human plasma and serum. Lamotrigine, carbamazepine, zonisamide and the internal standard ch
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