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Simulation and 3D display of DNA-histone complexes

✍ Scribed by H H Ohlenbusch; GDaney de Marcillac; H Bosshard

Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
296 KB
Volume
4
Category
Article
ISSN
0263-7855

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## Abstract The formation of complexes between cationic polymeric micelles of PS‐__b__‐PQ2VP amphiphilic block copolymers and DNA molecules in aqueous solutions is investigated at pH = 7. The physicochemical characteristics of the β€œpolyplexes” at different DNA/polymer ratios were characterized in t

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Conditions were studied under which aggregated complexes of histone F1 with DNA display a circular dichroic spectrum of nonconservat.ive type characterized by two intense negative maxima a t 269 nm and 209 nm. It was found that the intensity of the longwave band depends directly on the content of gu