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Simple synthesis of 4-aryl-6-styryl-1,2,3,4-tetrahydropyrimidin-2-ones by the alkaline hydrolysis of Biginelli compounds

✍ Scribed by Anatoly D. Shutalev; Alexey N. Aksionov


Book ID
111730547
Publisher
Royal Society of Chemistry
Year
2005
Tongue
English
Weight
123 KB
Volume
15
Category
Article
ISSN
0959-9436

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Biginelli-like three component reaction:
✍ Javad Azizian; Ali A. Mohammadi; M. Kohshari; Ali R. Karimi; Mohammad R. Mohamma πŸ“‚ Article πŸ“… 2007 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 243 KB

## Abstract magnified image In the context of our high‐throughput organic synthesis program, we have studied the reactivity of special β‐keto esters toward the Biginelli reaction. We have found that a diethyl‐3‐oxoglutarate reacts with one molecule of urea and one molecule of aldehyde under solven