Simple formula to predict response to peginterferon alpha2b and ribavirin combination therapy in genotype 1 chronic hepatitis C patients with high viral loads
β Scribed by Yoshito Itoh; Takeshi Nishimura; Hiroaki Hashimoto; Kanji Yamaguchi; Toshihisa Niimi; Chihiro Yokomizo; Hideki Fujii; Masahito Minami; Kohichiroh Yasui; Hironori Mitsuyoshi; Takeshi Okanoue; Tetsuo Takehara; Yoichi Hiasa; Morikazu Onji; Toshikazu Yoshikawa
- Book ID
- 118088363
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 237 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1386-6346
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## Abstract For chronic hepatitis C virus (HCV) infection, evaluation of response to peginterferon (PEGβIFN) plus ribavirin (RBV) therapy based on viral kinetics is useful as an early predictor of treatment efficacy, but the underlying mechanisms of the different viral kinetics to treatment are sti
## Abstract Variation at the ILβ28B locus was recently reported to be a significant predictive factor of viral response to pegylatedβinterferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including ILβ28B polymorphism rs8099917 and v