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583 Development and validation of a simple model to predict response to peginterferon plus ribavirin combination therapy in genotype 1 chronic hepatitis C


Book ID
117374089
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
226 KB
Volume
42
Category
Article
ISSN
0168-8278

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Development and validation of two models
✍ Eva MartΓ­nez-Bauer; Javier Crespo; Manuel Romero-GΓ³mez; Ricardo Moreno-Otero; Ri πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 250 KB πŸ‘ 1 views

Early prediction of response to therapy in genotype 1 chronic hepatitis C is difficult. Two predictive models, a pretreatment scoring model (PreT-SM) and a fourth week of therapy scoring model (4w-SM) were constructed in a cohort of 104 patients from a single center (estimation cohort) and validated

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## Abstract Variation at the IL‐28B locus was recently reported to be a significant predictive factor of viral response to pegylated‐interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL‐28B polymorphism rs8099917 and v