Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis
β Scribed by Masayuki Kurosaki; Naoya Sakamoto; Manabu Iwasaki; Minoru Sakamoto; Yoshiyuki Suzuki; Naoki Hiramatsu; Fuminaka Sugauchi; Hiroshi Yatsuhashi; Namiki Izumi
- Book ID
- 106180739
- Publisher
- Springer Japan
- Year
- 2010
- Tongue
- English
- Weight
- 460 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0944-1174
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We read with great interest the article published in a recent issue of HEPATOLOGY. 1 Shirakawa et al. enrolled 120 patients with chronic hepatitis C (CHC) infected with genotype 1 hepatitis C virus (HCV-1) and high baseline viral loads (HVL), defined by HCV RNA levels Υ 10 5 international units (IU)
## Abstract Variation at the ILβ28B locus was recently reported to be a significant predictive factor of viral response to pegylatedβinterferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including ILβ28B polymorphism rs8099917 and v