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Prediction of response to pegylated interferon/ribavirin combination therapy for chronic hepatitis C genotype 1b and high viral load

✍ Scribed by Soo Ryang Kim, Ahmed El-Shamy, Susumu Imoto, Ke Ih Kim, Yoshi-hiro Ide, Lin Deng, Ikuo Shoji, Yasuhito Tanaka, Yutaka Hasegawa, Mitsuhiro Ota, Hak Hotta


Book ID
111936959
Publisher
Springer Japan
Year
2012
Tongue
English
Weight
262 KB
Volume
47
Category
Article
ISSN
0944-1174

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## Abstract Patients with high viral load (β‰₯1.0 × 10^5^ IU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve high sustained virological response rates to interferon (IFN)/ribavirin combination therapy. Previous studies suggested that pretreatment amino acid (aa) substitution patterns in the