on behalf of the MErimepodib TRiple cOmbination (METRO) study group Merimepodib (MMPD) is an orally administered, inosine monophosphate dehydrogenase inhibitor that has shown antiviral activity in nonresponders with chronic hepatitis C (CHC) when combined with pegylated interferon alfa 2a (Peg-IFN-a
Chronic hepatitis C genotype 6 responds better to pegylated interferon and ribavirin combination therapy than genotype 1
β Scribed by Owen T-Y Tsang; Jonpaul S-T Zee; Jacky M-C Chan; Reggie S-T Li; Yee-Man Kan; Francis T-W Li; Fu-Hang Lo; David A Chow; Kent W-L Cheung; Kam-Hon Chan; Yat-Wah Yeung; Fook-Hong Ng; Michael K-K Li; Wai-Keung Kwan; Thomas S-T Lai
- Book ID
- 108952587
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 159 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0815-9319
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Hepatitis B virus (HBV) genotype and precore/core promoter mutations have been implicated in spontaneous and interferon alfa (IFN-+related hepatitis B e antigen (HBeAg) seroconversion. We performed a retrospective analysis of a previously reported randomized controlled trial to determine the effects
## Abstract The safety and efficacy of pegylated interferon (PEGβIFN) alfaβ2a and ribavirin were studied among patients treated for genotype 4 chronic hepatitis C. Ninetyβfive patients with chronic hepatitis C genotype 4 were treated with PEGβIFN alfaβ2a (180βΒ΅g/week) plus ribavirin (β₯11βmg/kg/day)