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Simple and Efficient Synthesis of 3,4-Dihydro-2-pyridones via Novel Solid-Supported Aza-Annulation

โœ Scribed by Wagman, Allan S.; Wang, Liang; Nuss, John M.

Book ID
121504190
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
185 KB
Volume
65
Category
Article
ISSN
0022-3263

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โœ Anil K. Verma; Summon Koul; Ajay P. S. Pannu; Tej K. Razdan ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons โš– 32 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

A versatile and efficient synthesis of (
A versatile and efficient synthesis of (2S)-2-(hydroxymethyl)-N-Boc-2,3-dihydro-4-pyridone
โœ A Shashidhar Kumar; B Haritha; B Venkateswara Rao ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 81 KB

A versatile and efficient method for the preparation of (2S)-2-(hydroxymethyl)-N-Boc-2,3-dihydro-4-pyridone from L-(-)-phenylalanine 2 utilising the aromatic system as a masked b-keto aldehyde was developed. The key step in the sequence is an intramolecular cyclisation of 6 to give 2,3-dihydropyridi