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Simple Analysis of Plasmalogens in Erythrocytes Using Gas Chromatography/Mass Spectrometry with Selected-ion Monitoring Acquisition

✍ Scribed by U. Caruso

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
285 KB
Volume
10
Category
Article
ISSN
0951-4198

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✦ Synopsis

Plasmalogens are a unique class of ether-phospholipids whose role, even though not fully defined, is essential. Their biosynthesis starts in peroxisomes, therefore, plasmalogen analysis is fundamental in the study of peroxisomal disorders. The present work reports a simple method for plasmalogen determination in erythrocytes for use in the study of peroxisomal disorders in humans; the procedure is based on two other methods that have previously been reported and employs GUMS for separation and detection.

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