A ferrocenylphosphine-silver-isocyanoacetate complex was investigated as a model compound for catalytic species in gold-catalyzed aldol reaction. 'H{lH} NOE studies of the silver complex indicated that terminal amino group of pendant side chain of the ferrocenylphosphine ligand is located close to a
Silver(I)-catalyzed asymmetric aldol reaction of isocyanoacetate
โ Scribed by Tamio Hayashi; Yasuhiro Uozumi; Akiko Yamazaki; Masaya Sawamura; Hitoshi Hamashima; Yoshihiko Ito
- Book ID
- 103403797
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 276 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
During last two decades, a growing number of papers dealing with fluorine-containing amino acids have demonstrated the usefulness of these amino acids in the design of novel biologically active compounds as well as in the study of the biological chemistry. 2 A large number of fluoroamino acids have
summsry: Asymmetric aldol reaction of a-ketoesters (RCOCCCMe: R = Me, i-Bu, ph) with methyl isocyanoacetate or N,N-dimethyl-a-isocyanoacetamide in the presence of 1 molX of a chiral (arinoalkyl)ferrocenylphosphine-gold(I) catalyst proceeded with high enantioselectivity to give corresponding oxazolin