Most characteristics of matrix-assisted laser desorption/ionization (MALDI) are ideal for the analysis of biomolecules. New preparation techniques have dramatically increased mass accuracy and resolution, making MALDI a high-performance mass spectrometric technique for peptide mass analysis. Attempt
Silver nanoparticles as matrix for laser desorption/ionization mass spectrometry of peptides
β Scribed by Lin Hua; Jianrong Chen; Liya Ge; Swee Ngin Tan
- Publisher
- Springer Netherlands
- Year
- 2007
- Tongue
- English
- Weight
- 230 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1388-0764
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## Abstract Matrix assisted laser desorption/ionization (MALDI) is a soft ionization mass spectrometric method that has become a preeminent technique in the analysis of a wide variety of compounds including polymers and proteins. The main drawback of MALDI is that it is difficult to analyze low mol
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) was used to explore noncovalent interactions between different peptides and ribose nucleic acids (RNAs). One RNA was mixed together with two or more peptides or vice versa to compare the different effects of the molecules for n
One problem of matrix-assisted laser desorption ionization coupled to time-of-flight mass spectrometry is the moderate mass accuracy that typically can be obtained in routine applications, Here we report improved mass accuracy for peptides, even when low amounts and complex peptide mixtures are used
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