✦ LIBER ✦

Developments in matrix-assisted laser desorption/ionization peptide mass spectrometry

✍ Scribed by Matthias Mann; Gert Talbo

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 749 KB
Volume: 7
Category: Article
ISSN: 0958-1669
DOI: 10.1016/s0958-1669(96)80089-9

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✦ Synopsis

Most characteristics of matrix-assisted laser desorption/ionization (MALDI) are ideal for the analysis of biomolecules. New preparation techniques have dramatically increased mass accuracy and resolution, making MALDI a high-performance mass spectrometric technique for peptide mass analysis. Attempts to obtain amino acid sequence information by MALDI have been partially successful. The technique has been put to novel uses in protein primary structure characterization.

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