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Silicagel supported sodium hydrogensulfate as a heterogenous catalyst for high yield synthesis of 3,4-dihydropyrimidin-2 (1H)-ones

✍ Scribed by M. Adharvana Chari; K. Syamasundar

Book ID
108211362
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
66 KB
Volume
221
Category
Article
ISSN
1381-1169

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## Abstract magnified image DDQ catalyzes efficiently the three‐component condensation reaction of aldehyde, β‐ketoester and urea in refluxing acetonitrile to afford the corresponding dihydropyrimidinones. Compared to the classical Biginelli reaction conditions, this new approach consistently has