✦ LIBER ✦

Dichloro dicyano quinone (DDQ) as coupling reagent for high yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones

✍ Scribed by D. Shobha; M. Adharvana Chari; P. Sadanandam; K. Mukkanti

Publisher: Journal of Heterocyclic Chemistry
Year: 2008
Tongue: English
Weight: 173 KB
Volume: 45
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570450448

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

magnified image

DDQ catalyzes efficiently the three‐component condensation reaction of aldehyde, β‐ketoester and urea in refluxing acetonitrile to afford the corresponding dihydropyrimidinones. Compared to the classical Biginelli reaction conditions, this new approach consistently has the advantage of excellent yields (80‐92%) and short reaction times 1.5‐2.5 h.

📜 SIMILAR VOLUMES

ChemInform Abstract: Dichloro Dicyano Qu

ChemInform Abstract: Dichloro Dicyano Quinone (DDQ) as Coupling Reagent for High Yield Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones.

✍ D. Shobha; M. Adharvana Chari; P. Sadanandam; K. Mukkanti 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 28 KB

Cu(OTf)2: A Reusable Catalyst for High-Y

Cu(OTf)2: A Reusable Catalyst for High-Yield Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones.

✍ A. S. Paraskar; G. K. Dewkar; A. Sudalai 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 131 KB 👁 1 views

ZrOCl2×8H2O as an Efficient Reagent for

ZrOCl2×8H2O as an Efficient Reagent for the Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2-(1H)-ones.

✍ Farhad Shirini; Mohammad Ali Zolfigol; Esmail Mollarazi 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 22 KB 👁 2 views

Trimethylsilyl Chloride: A Facile and Ef

Trimethylsilyl Chloride: A Facile and Efficient Reagent for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones.

✍ Yulin Zhu; Yuanjiang Pan; Shenlin Huang 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

Scandium(III) Triflate as an Efficient a

Scandium(III) Triflate as an Efficient and Reusable Catalyst for Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones.

✍ Surya K. De; Richard A. Gibbs 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 17 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Bismuth Oxide Perchlorate Catalyzed Effi

Bismuth Oxide Perchlorate Catalyzed Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones: An Improved High Yielding Protocol for the Biginelli Reaction.

✍ Y. Thirupathi Reddy; P. Narsimha Reddy; B. Sunil Kumar; G. V. P. Rao; B. Rajitha 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 17 KB 👁 1 views