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Silencing of CT120 by antisense oligonucleotides could inhibit the lung cancer cells growth

✍ Scribed by Z. Li; S. Shao; S. Xie; F. Jiao; Y. Ma; S. Shi


Book ID
107526303
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
396 KB
Volume
179
Category
Article
ISSN
1863-4362

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Human pancreatic cancers overexpress the epidermal growth factor (EGF) receptor (EGFR) and all 5 ligands that bind to this receptor, including amphiregulin. It is not known, however, whether amphiregulin contributes in an autocrine manner to enhance pancreatic cancer cell growth. Therefore, we used