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Significance of Unconventional Peripheral CD4+CD8dim T Cell Subsets

✍ Scribed by Lambert Claude; Ibrahim Mohammad; Iobagiu Cristina; Genin Christian


Publisher
Springer
Year
2005
Tongue
English
Weight
527 KB
Volume
25
Category
Article
ISSN
0271-9142

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Peripheral tolerance is induced under conditions that avoid activation of antigen-presenting cells (APCs) to release cytokines. Such tolerance occurs in both CD4+ T helper (Th)-cell subsets (Th1 and Th2), probably because it is induced in precursor cells. By contrast, activation of APCs to release c