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Activated CD4+and CD8+T-cell subsets in Wegener's granulomatosis

✍ Scribed by M. Schlesier; T. Kaspar; J. Gutfleisch; G. Wolff-Vorbeck; H. -H. Peter


Publisher
Springer
Year
1995
Tongue
English
Weight
704 KB
Volume
14
Category
Article
ISSN
0172-8172

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## Abstract ## Objective Accumulating data support the role of regulatory T cells, a subset of CD4+ T cells that expresses CD25^high^ and the transcription factor forkhead box P3 (FoxP3), in controlling and preventing autoimmunity. In Wegener's granulomatosis (WG), an autoimmune vasculitis, up‐reg

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