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Significance of non-standard Philadelphia chromosomes in chronic granulocytic leukaemia

โœ Scribed by Potter, A M; Watmore, A E; Cooke, P; Lilleyman, J S; Sokol, R J

Book ID
109835202
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
578 KB
Volume
44
Category
Article
ISSN
0007-0920

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๐Ÿ“œ SIMILAR VOLUMES

Molecular biology of Philadelphia chromo
Molecular biology of Philadelphia chromosome in chronic granulocytic leukaemia and acute lymphoblastic leukaemia
โœ S. Eridani; L. M. Wiedemann; L. C. Chan; R. G. Dalton; K. K. Karhi ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 447 KB

In classical t(9;22) translocation, as observed in chronic granulocytic leukemia (CGL), a hybrid DNA unit is produced, including a rearranged PHL gene, previously known as bcr (breakpoint cluster region) plus the translocated c-abl gene from chromosome 9: a hybrid bcr-abl protein, p210 is formed, wi