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Shortening velocity, myosin light chain phosphorylation and Ca2+dependence of force during metabolic inhibition in smooth muscle of rat portal vein

โœ Scribed by EKMEHAG, B. L. ;HELLSTRAND, P.


Book ID
114869651
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
787 KB
Volume
136
Category
Article
ISSN
0001-6772

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Effects of a myosin light chain kinase i
โœ Makoto Takayama; Hiroshi Ozaki; Hideaki Karaki ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 870 KB

Biochemical studies have shown that wortmannin is an inhibitor of myosin light chain (MLC) kinase (Nakanishi et al. (1992) J. Biol. Chem. 267: 2157-2163). To investigate the role of MLC kinase in smooth muscle contractions, we examined the effects of wortmannin on isolated smooth muscles of the rat