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Short telomeres and high telomerase activity in T-cell prolymphocytic leukemia

✍ Scribed by Röth, A; Dürig, J; Himmelreich, H; Bug, S; Siebert, R; Dührsen, U; Lansdorp, P M; Baerlocher, G M


Book ID
110058478
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
280 KB
Volume
21
Category
Article
ISSN
0887-6924

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Telomerase activity and telomere length
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## BACKGROUND. Telomeres shorten with successive cell divisions in normal somatic cells. Telomerase is a ribonucleoprotein enzyme associated with cellular proliferation and plays an important role in maintaining the stability of chromosomes and the length of DNA telomeres. Telomerase activity has